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DNA Isolation

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Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format

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Consent process for US-based family reference DNA samples.

Sara H Katsanis¹, Lindsey Snyder¹, Kelly Arnholt²

¹Duke Initiative for Science and Society, Duke University, Durham, NC 27710, USA.

Forensic Science International. Genetics

|November 7, 2017

Summary

This summary is machine-generated.

Standardizing DNA collection consent for families in missing persons investigations is crucial. This study proposes model language to improve communication and ensure informed consent during these sensitive procedures.

Keywords:

DNA identification Disaster victim identification Family reference samples Informed consent Mass disaster Mass fatalities Missing persons

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Area of Science:

Forensic Science
Genetics
Legal Medicine

Background:

DNA collection from relatives is vital for missing persons and mass fatality investigations.
Current consent procedures for family DNA samples are inconsistent and lack standardization.
Existing guidelines for mass fatalities and missing persons do not cover consent for living family members.

Purpose of the Study:

To develop standardized consent language for collecting DNA from family members in missing persons and mass fatality investigations.
To address the lack of clear guidelines for obtaining consent from living relatives of potential victims.
To create a foundation for improved consent practices in forensic investigations.

Main Methods:

Reviewed U.S. laws, international guidelines, and best practices related to DNA collection and consent.
Analyzed existing DNA consent forms used for family members.
Drafted model consent language based on biobank practices and tested it for feedback and readability.

Main Results:

Identified significant variability in current consent procedures.
Developed and tested model consent language for clarity and effectiveness.
Gathered feedback from students and the general population on consent options and hypothetical agreement.

Conclusions:

There is a need for standardized consent practices in missing persons and mass fatality investigations.
The proposed model language can enhance communication and ensure informed consent.
This work provides a foundation for future improvements in forensic DNA collection consent processes.