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Healthy management of very early adolescent pregnancy
1West Virginia University-Charleston Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, 800 Pennsylvania Avenue, Charleston, WV 25302; Phone: 304-388-1599; Fax: 304-388-2915; byron.calhoun@camc.org.
Insights
Very early pregnancies (mothers < 15 years) show increased risks for low birth weight, preterm birth, and small for gestational age infants. However, outcomes are not universally grim, with decreased risks for cesarean delivery and diabetes.
Area of Science:
- Maternal-fetal medicine
- Adolescent health
- Perinatal epidemiology
Background:
- Very early pregnancy (mothers < 15 years) is often associated with adverse birth outcomes.
- These include low birth weight (LBW), preterm birth (PTB), small for gestational age (SGA) infants, stillbirth, and neonatal mortality.
Purpose of the Study:
- To systematically review the risks of LBW, PTB, SGA, stillbirth, and neonatal mortality in infants born to mothers younger than 15 years.
- To compare these risks against a control group of older pregnant individuals.
Main Methods:
- Searched Medline, Embase, CINAHL, and bibliographies for relevant English-language studies.
- Included studies reporting birth outcomes for mothers < 15 years with a comparison cohort of older gravidas.
- Assessed study quality for biases in sample selection, age cohorts, confounder adjustment, and outcome assessment.
Main Results:
- Analyzed 21 studies meeting inclusion criteria from 46 identified.
- Found increased risks for SGA, LBW (< 2,500g), and PTD (< 37 weeks) in very early adolescent pregnancies.
- Observed decreased risks for diabetes mellitus (DM) and cesarean section, with conflicting risks for preeclampsia and instrumental delivery.
Conclusions:
- Very early adolescent pregnancies (< 15 years) do not universally result in grim outcomes.
- These pregnancies show decreased risks for cesarean delivery, DM, and active phase disorders.
- Adverse outcomes may be mitigated with improved, adolescent-focused antenatal care.
Background:
Very Early Pregnancy (< 15 years at delivery) is suggested as a risk factor for adverse pregnancy outcome including low birth weight (LBW), preterm birth (PTB), small for gestational age (SGA) infants, stillbirth, and neonatal mortality.
Objective:
To systematically review the risk of an infant being born LBW/ PTB/SGA/stillbirth or neonatal mortality among patients < 15 years of age. Search strategy: Medline, Embase, CINAHL, and bibliographies of identified articles were searched for English language studies.
Selection Criteria:
Selection criteria: Studies reporting birth outcomes to mothers < 15 years of age with an appropriate control group of older gravidas. Data collection and analysis: A single reviewer collected data and assessed the quality of the studies for biases in sample selection, correct age cohorts, confounder adjustment, analytical, outcome assessments, and attrition. Main results: Forty-six studies were located with very early adolescent pregnancy. Of these, only 21 papers had the correct age group (< 15 years) with a comparison cohort. The studies found in the very early adolescent pregnancy: Increased risk of SGA; Increased risk of LBW < 2,500 gms; Increased risk of PTD < 37 weeks; Decreased risk of DM; Decreased risk of cesarean section; Decreased risk of use of pitocin/active phase length; Conflicting risks for Preeclampsia/VLBW/Episiotomy/instrumental delivery rates.
Selection Criteria:
Very early adolescent pregnancies (< 15 years) do not have universally grim outcomes as normally quoted. Very early adolescent pregnancies have decreased risk of cesarean delivery, DM, and of active phase disorders. Further, many of the adverse outcomes may be ameliorated with earlier, adolescent-focused, and improved antenatal care.
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