Healthy management of very early adolescent pregnancy

Byron C Calhoun1

  • 1West Virginia University-Charleston Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, 800 Pennsylvania Avenue, Charleston, WV 25302; Phone: 304-388-1599; Fax: 304-388-2915; byron.calhoun@camc.org.

Issues in Law & Medicine
|November 7, 2017
PubMed

Insights

Very early pregnancies (mothers < 15 years) show increased risks for low birth weight, preterm birth, and small for gestational age infants. However, outcomes are not universally grim, with decreased risks for cesarean delivery and diabetes.

Area of Science:

  • Maternal-fetal medicine
  • Adolescent health
  • Perinatal epidemiology

Background:

  • Very early pregnancy (mothers < 15 years) is often associated with adverse birth outcomes.
  • These include low birth weight (LBW), preterm birth (PTB), small for gestational age (SGA) infants, stillbirth, and neonatal mortality.

Purpose of the Study:

  • To systematically review the risks of LBW, PTB, SGA, stillbirth, and neonatal mortality in infants born to mothers younger than 15 years.
  • To compare these risks against a control group of older pregnant individuals.

Main Methods:

  • Searched Medline, Embase, CINAHL, and bibliographies for relevant English-language studies.
  • Included studies reporting birth outcomes for mothers < 15 years with a comparison cohort of older gravidas.
  • Assessed study quality for biases in sample selection, age cohorts, confounder adjustment, and outcome assessment.

Main Results:

  • Analyzed 21 studies meeting inclusion criteria from 46 identified.
  • Found increased risks for SGA, LBW (< 2,500g), and PTD (< 37 weeks) in very early adolescent pregnancies.
  • Observed decreased risks for diabetes mellitus (DM) and cesarean section, with conflicting risks for preeclampsia and instrumental delivery.

Conclusions:

  • Very early adolescent pregnancies (< 15 years) do not universally result in grim outcomes.
  • These pregnancies show decreased risks for cesarean delivery, DM, and active phase disorders.
  • Adverse outcomes may be mitigated with improved, adolescent-focused antenatal care.
Abstract

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