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Rapid Cocaine-Induced Spine Changes in the Nucleus Accumbens

Rajtarun Madangopal1

  • 1Neuronal Ensembles in Addiction Section, Behavioral Neuroscience Branch, Intramural Research Program of the National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland.

Biological Psychiatry
|November 8, 2017
PubMed
Abstract

No abstract available in PubMed .

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CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
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