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Gastric preparation for magnetically controlled capsule endoscopy: A prospective, randomized single-blinded
Shu-Guang Zhu1, Yang-Yang Qian1, Xin-Ying Tang1
1Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China.
Summary
For optimal gastric mucosal image quality during magnetically controlled capsule endoscopy (MCE), water with simethicone is recommended. Adding pronase to the preparation did not provide additional benefits.
Area of Science:
- Gastroenterology
- Medical Imaging
- Endoscopy
Background:
- Magnetically controlled capsule endoscopy (MCE) is an emerging diagnostic tool.
- Standardized gastric preparation protocols for MCE are not well-established.
- Optimal preparation is crucial for effective gastric visualization.
Purpose of the Study:
- To identify an optimal standardized gastric preparation regimen for MCE.
- To compare the efficacy of different pre-MCE gastric preparations.
Main Methods:
- A randomized controlled trial involving 120 patients undergoing MCE.
- Patients were assigned to three groups: water alone, water with simethicone, or water with simethicone and pronase.
- Image quality was quantitatively assessed using cleanliness and visualization scores.
Main Results:
- Gastric preparation with water and simethicone (Group B) and water, simethicone, and pronase (Group C) significantly improved image quality compared to water alone (Group A).
- No significant difference in image quality or MCE diagnostic yield was observed between the simethicone and simethicone-plus-pronase groups.
- The addition of pronase did not enhance gastric mucosal visualization or MCE findings.
Conclusions:
- Simethicone, when taken with water before MCE, yields optimal gastric mucosal image quality.
- Pronase does not offer additional benefits to gastric preparation for MCE.
- Standardized MCE protocols should consider simethicone for improved gastric imaging.