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Facile Preparation of 4-Substituted Quinazoline Derivatives
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The synthesis of 2,3,6-trisubstituted 1-oxo-1,2-dihydroisoquinolines as potent CRTh2 antagonists

Xianhai Huang1, Ashwin Rao1, Wei Zhou1

  • 1Discovery Chemistry, MRL, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA.

Bioorganic & Medicinal Chemistry Letters
|November 8, 2017
PubMed

Keywords:
1-Oxo-1,2-dihydroisoquinolineAsthmaCRTh(2) antagonistsIntramolecular cyclizationIsoquinolinoneRespiratory diseases

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