Recent advances in detection of metastatic testicular cancer

The recent advances in therapy of testicular cancer have made the early diagnosis and localization of metastases desirable and rewarding. The objectives of this presentation are to describe 1) the utilization of selective venous catheterization of venous outflow from the tumour or organ containing tumour producing minute amounts of α subunit or intact molecule of hCG; 2) the utilization of a new liposoluble contrast material that is picked up by the reticuloendothelial system of the liver therefore enhancing the computed tomographic (CT) images of liver metastases for earlier detection compared to the conventional CT images; and 3) the utilization of radioimmunodetection of AFP- and hCG-producing tumours by preparing specific and sensitive radioactive antibody labelled with ¹³¹ I, the deposition of which may be localized by conventional scintigraphy.