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Updated: Feb 19, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Predictive factors of hyperglycemia in hospitalized adults receiving total parenteral nutrition
Teresa García Martínez1, Belén Montañes Pauls1, Ana María Vicedo Cabrera2
1Servicio de Farmacia, Hospital General Universitario de Castellón, Castellón de la Plana. garciamartinez.t@gmail.com.
Objective:
To know those predictive factors of hyperglycemia that could guide us the design of a parenteral nutrition and it could avoid later complications associated with it. Methods: A prospective observational study was designed; adult hospitalized patients who received total parenteral nutrition at least 48 hours were included. Nutritional and pharmacotherapeutic follow-up were performed according to usual practice. Variables collected included demographic, clinical, analytical and nutrition and pharmacotherapy. Results: Fifty-eight patients were included, with 28 patients (48.3%) with glucose restriction. This intervention was statistically associated with elevated glycemia prior to parenteral nutrition (OR: 1.38, 95% CI 1.11-1.73, p = 0.004) and BMI (OR: 1.29, 95% CI 1.05-1.58, p = 0.014), with more frequent intervention was in patients with BMI > 25 (overweight and obese) (OR: 10.00; 95% CI 1.15-86.95, p = 0.037).
Conclusions:
Pre-parenteral glycemic values, diabetes and BMI values > 25 are predictors of hyperglycemia, so a early intervention to prevent and correct hyperglycemia may improve clinical outcomes in patients with parenteral nutrition.
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