Novel rhodamine Schiff base type naked-eye fluorescent probe for sensing Fe3+ and the application in cell
Xia Chen1, Wei Sun1, Yinjuan Bai1
1Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, Shannxi 710127, PR China.
Abstract:
Three rhodamine schiff-base type fluorescent sensors R1-R3 for detecting iron ion (Fe3+), 2-furanacrolein rhodamine hydrazone (R1), furfural rhodamine hydrazone (R2) and 2-furanacrolein rhodamine ethylenediamine (R3) have been synthesized by using rhodamine B derivatives and furan derivatives as staring materials. And their recognition abilities for Fe3+ were studied by fluorescence spectroscopy. The result showed that R1 is a best selective probe for Fe3+ over other metal ions in EtOH/H2O (1:1, v/v) due to having 2-furanacrolein for unique space coordination structural. The recognition of Fe3+ and mechanism of the sensor were characterized and determined by fluorescence spectra and Fukui function. And the fluorescence intensity of the probe R1 for Fe3+ was proportional to its concentration with the linear correlation coefficient of 0.9965 and the binding constant of 7.66×104M-1. And the cell imaging experiment indicated a successful application of the probe R1 for Fe3+ in living cell.
