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Identifying a better strategy for ad hoc percutaneous coronary intervention in patients with anticipated unfavorable
Gregory A Sgueglia1, Daniel Todaro2, Antonella De Santis1
1Sant'Eugenio Hospital, Rome, Italy.
Insights
For women with small radial arteries undergoing ad hoc percutaneous coronary intervention (PCI), a modified 6 French workflow using 5 French diagnostic catheters is more effective than a standard 6 French approach.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Access
Background:
- Transradial percutaneous coronary intervention (PCI) offers advantages over transfemoral PCI.
- A 6 French workflow is common for ad hoc PCI, potentially limiting options for patients with small radial arteries.
Purpose of the Study:
- To compare a standard 6 French workflow with a modified 5 French diagnostic catheter workflow for ad hoc PCI in women under 160cm.
Main Methods:
- 120 women (<160cm) were evaluated using either a full 6 French workflow or a modified workflow (6F sheath, 5F diagnostic catheters, 6F guiding catheter).
- Outcomes measured included radial spasm, access site switch, and time to guidewire lesion crossing.
Main Results:
- Radial spasm (43% vs 25%) and access site switch (11% vs 2%) were more frequent with the 6 French diagnostic catheters.
- Time to guidewire lesion crossing was significantly longer with the 6 French diagnostic catheters (23±11min vs 16±7min).
Conclusions:
- A modified workflow using a 6 French sheath, 5 French diagnostic catheters, and a 6 French guiding catheter is a more straightforward and effective strategy for ad hoc PCI in patients with anticipated unfavorable radial access.
Background:
Transradial percutaneous coronary intervention (PCI) offers important advantages over transfemoral PCI, including better outcomes. However, when there is indication to ad hoc PCI, a 6 French workflow is a common default strategy, hence potentially influencing vascular access selection in patients with anticipated small size radial artery.
Methods:
A multidimensional evaluation was performed to compare two ad hoc interventional strategies in women <160cm: a full 6 French workflow (namely 6 French introducer sheath, diagnostic catheters and guiding catheter) with a modified workflow consisting in the use of 5 French diagnostic catheters preceded by the placement of a 6 French sheath introducer and followed by a 6 French guiding catheter use for PCI.
Results:
Overall 120 women (68±11years) were enrolled in the study. Coronary angiography has been performed using 5 French or 6 French diagnostic catheters in 57 (47.5%) and 63 (52.5%) cases, respectively. Radial spasm and switch to another access occurred more frequently among women who underwent coronary angiography with 6 French rather than 5 French diagnostic catheters (43% vs. 25%, p=0.03 and 2% vs. 11%, p=0.04, respectively). Total time to guidewire lesion crossing was also significantly higher when PCI has been preceded by 6 French rather than 5 French coronary angiography (23±11min vs 16±7min, p=0.013).
Conclusions:
In patients with anticipated unfavorable radial access, a workflow consisting in 6 French introducer sheath placement, 5 French coronary angiography, and 6 French coronary intervention is on multiple parameters the most straightforward and effective strategy.
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