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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

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Published on: February 6, 2019

Universal field matching in craniospinal irradiation by a background-dose gradient-optimized method.

Erik Traneus¹, Nicola Bizzocchi², Francesco Fellin²

¹RaySerach Laboratories, Stockholm, Sweden.

Journal of Applied Clinical Medical Physics

|November 9, 2017

Summary

A new gradient-optimized technique using background dose improves field junction planning in craniospinal irradiation for both proton and photon therapy, ensuring homogeneous target coverage.

Keywords:

VMAT craniospinal irradiation field junction proton therapy

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Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

Radiation Oncology
Medical Physics
Radiotherapy Planning

Background:

Traditional feathering methods for craniospinal irradiation junctions are being replaced by gradient-optimized techniques.
Effective planning of junctions is crucial for precise dose delivery in complex radiotherapy cases.

Purpose of the Study:

To describe a novel gradient-optimized technique for planning field junctions in craniospinal irradiation.
To introduce a method utilizing a background dose for improved junction gradient optimization.

Main Methods:

Treatment planning was performed using RayStation software on pediatric patient CT scans.
Both proton (pencil beam scanning) and photon (volumetric modulated arc therapy) plans were created with three isocenters.
An 'in silico' background dose was used to guide inverse optimization of cranial, lower-spinal, and upper-spinal beams.

Main Results:

The technique generated perfect linear dose gradients in junction regions for both proton and photon plans.
Optimized beams created complementary gradients, resulting in homogeneous target dose coverage.
Final dose distributions demonstrated effective junctional dose conformity.

Conclusions:

The described technique simplifies achieving high-quality dose gradients at junctions in craniospinal irradiation.
This method is applicable to both photon and proton therapy.
The technique can be implemented in treatment planning systems that support background dose management.