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Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH

Published on: April 20, 2021

Shear wave liver elastography.

Richard G Barr^1,2

¹Northeastern Ohio Medical University, Rootstown, OH, USA. rgbarr@zoominternet.net.

Abdominal Radiology (New York)

|November 9, 2017

Summary

This summary is machine-generated.

Chronic liver disease can lead to cirrhosis. Ultrasound elastography offers a non-invasive way to stage liver fibrosis, with point shear wave (p-SWE) and 2D-SWE showing promise over transient elastography (TE).

Keywords:

Cirrhosis Liver stiffness Point shear wave elastography Real-time shear wave elastography Shear wave elastography

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Area of Science:

Hepatology
Medical Imaging
Diagnostic Techniques

Background:

Chronic liver disease is a global health issue, often progressing to cirrhosis.
Cirrhosis can cause portal hypertension, hepatic insufficiency, and hepatocellular carcinoma.
Accurate staging of liver fibrosis is crucial for prognosis, treatment, and assessing reversibility.

Purpose of the Study:

To review the background of chronic liver disease.
To discuss various ultrasound elastography techniques for staging liver fibrosis.
To provide guidance on performing and interpreting elastography examinations.

Main Methods:

Review of existing literature on chronic liver disease and ultrasound elastography.
Description of transient elastography (TE), point shear wave elastography (p-SWE), and 2D shear wave elastography (2D-SWE).
Comparison of the accuracy and reliability of different elastography methods.

Main Results:

Liver biopsy was the traditional method for staging fibrosis.
Ultrasound elastography provides a non-invasive alternative for assessing liver fibrosis.
Current evidence suggests p-SWE is comparable to TE in reliability, and 2D-SWE is more accurate than TE.

Conclusions:

Ultrasound elastography techniques, particularly p-SWE and 2D-SWE, are valuable non-invasive tools for staging liver fibrosis.
These methods offer advantages over traditional liver biopsy.
Further understanding and application of these techniques can improve patient management in chronic liver disease.