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Practical issues in implementing whole-genome-sequencing in routine diagnostic microbiology

J W A Rossen1, A W Friedrich2, J Moran-Gilad3

  • 1University of Groningen, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands; European Society for Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Genomic and Molecular Diagnostics (ESGMD), Basel, Switzerland.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|November 9, 2017
PubMed
Summary

Implementing bacterial whole genome sequencing (WGS) in clinical microbiology requires careful management of workflows, quality control, and cost. Further development is needed to optimize turnaround time and data analysis for WGS to fully transform patient care.

Keywords:
Antimicrobial resistanceBacterial typingClinical microbiologyDiagnostic stewardshipMolecular diagnosticsNext generation sequencingQuality controlWhole genome sequencing

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