Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Clostridial bloodstream infections.

C W Ingram¹, J N Cooper

¹Department of Medicine, Fairfax Hospital, Falls Church, Va.

Southern Medical Journal

|January 1, 1989

Summary

Clostridial bloodstream infections are rare but serious, often occurring in patients with underlying conditions and a bowel source. These infections are frequently fatal, highlighting the need for vigilance in high-risk individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Risk of re-operation after outpatient distal hypospadias repair in a large, multistate cohort.

Journal of pediatric urology·2019

Same author

catena-Poly[zinc-μ(3)-{3,3'-[(1,7-dioxa-4,10-diaza-cyclo-dodecane-4,10-di-yl)bis-(methyl-ene)]dibenzoato}].

Acta crystallographica. Section E, Structure reports online·2013

Same author

Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia.

Leukemia·2011

Same author

Effects of commercial diazinon and imidacloprid on microbial urease activity in soil and sod.

Journal of environmental quality·2005

Same author

Findings of the 1998 Infectious Diseases Society of America membership survey.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2000

Same author

A microwave digestion-based determination of low molecular weight organic acids in Bayer process liquor.

Talanta·1995

Area of Science:

Microbiology
Infectious Diseases
Clinical Medicine

Background:

Clostridia are anaerobic bacteria that can cause serious infections.
Bloodstream infections (BSIs) are a significant cause of morbidity and mortality.
Understanding the epidemiology and clinical significance of specific pathogens in BSIs is crucial for patient management.

Observation:

A ten-year review of bloodstream isolates at a community teaching hospital identified Clostridia in less than 1% of positive cultures (26 episodes in 25 patients).
The vast majority of Clostridial BSIs were clinically significant, with 88% of patients having serious underlying medical conditions.
A bowel source was identified in 65% of cases.

Findings:

Clostridial BSIs are associated with high mortality rates, with 48% of infected patients dying.
Patients with serious underlying diseases are particularly vulnerable to severe outcomes from Clostridial BSIs.
The study underscores the clinical significance of Clostridia in bloodstream infections, especially in immunocompromised or critically ill patients.

Implications:

Early recognition and management of Clostridial BSIs are critical, particularly in patients with predisposing factors.
Further research into preventative strategies and targeted therapies for Clostridial BSIs may be warranted.
This data emphasizes the importance of considering Clostridia in the differential diagnosis of BSIs in patients with gastrointestinal pathology or severe comorbidities.

Related Experiment Videos