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Related Concept Videos

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Related Experiment Video

Updated: Feb 19, 2026

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
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Body Mass Index and Acute Ischemic Stroke Outcomes.

M Saini1, M Saqqur2, A Shuaib2

  • 11 Department of Medicine, Acute Stroke Unit, Changi General Hospital, Singapore.

International Journal of Stroke : Official Journal of the International Stroke Society
|November 10, 2017
PubMed
Summary

Being overweight or obese may improve outcomes after acute ischemic stroke. This study found lower mortality and better functional outcomes in overweight or obese stroke patients, though factors like age and gender play a role.

Keywords:
body mass indexischemicobesityoutcomesoverweightstroke

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Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Public Health

Background:

  • The relationship between body mass index (BMI) and acute ischemic stroke outcomes remains incompletely understood.
  • Existing research presents conflicting data on how BMI affects stroke recovery and survival.

Purpose of the Study:

  • To investigate the impact of body mass index (BMI) on short-term (90-day) outcomes following acute ischemic stroke.
  • To analyze the association between BMI categories and functional outcomes and mortality in stroke patients.

Main Methods:

  • Data from 4811 acute ischemic stroke patients were analyzed from the Virtual International Stroke Trials Archive.
  • Multivariate logistic regression and Cox proportional hazard analyses assessed BMI's effect on modified Rankin Scale scores and mortality.
  • Baseline body mass index records were utilized for the analysis.

Main Results:

  • Overweight (BMI 25-29.9 kg/m2) was linked to significantly reduced mortality (HR 0.59) and improved functional outcomes (OR 0.74) within 90 days.
  • Obesity (BMI ≥30 kg/m2) also showed a trend towards better outcomes, though not explicitly detailed in the provided text.
  • The influence of BMI on stroke outcomes was found to be modulated by patient age, gender, and the administration of thrombolytic therapy.

Conclusions:

  • Overweight and obese individuals experiencing acute ischemic stroke demonstrated better functional recovery and lower mortality rates.
  • The concept of an 'optimal' BMI for stroke patients is complex and influenced by demographic factors and treatment interventions.
  • Further research is warranted to refine BMI-based risk stratification and treatment strategies for acute ischemic stroke.