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The Complexities of Nocardia Taxonomy and Identification
Patricia S Conville1, Barbara A Brown-Elliott2, Terry Smith2
1Division of Microbiology Devices, Office of In-Vitro Diagnostics and Radiological Health, Center for Devices and Radiological Health, Food and Drug Administration, U.S. Department of Health and Human Services, Silver Spring, Maryland, USA patricia.conville@fda.hhs.gov.
Abstract:
Nocardia species are a complex group of organisms considered to belong to the aerobic actinomycetes. Of the validly described species, many have been implicated as the cause of serious human infections, especially in immunocompromised patients. The genus has a complicated taxonomic history; this is especially true for Nocardia asteroides, the type species of the genus and previously the most frequently reported nocardial taxon from human specimens. We provide background on the current taxonomy of Nocardia, with a focus on clinically relevant species, and discuss the currently available methods used to accurately identify isolates to the species, complex, or group level.
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