Related Experiment Video
Updated: Feb 19, 2026

Mouse Models of Periventricular Leukomalacia
Published on: May 18, 2010
Periventricular leukomalacia with -16 DS high myopia in a 2½ months old infant: A rare case presentation
Praveen Jeyaseelan1, Tulika Kar1, P Vijayalakshmi1
1Department of Pediatric Ophthalmology and Adult Strabismus, Aravind Eye Care System, Madurai, Tamil Nadu, India.
Abstract:
Periventricular leukomalacia (PVL) is coagulation necrosis of white matter seen in preterm, low birth weight (LBW) infants and associated with a range of ocular manifestations. We report a case of 2½ months old (47 weeks gestational age) female infant with PVL associated with bilateral high myopia (-16 DS). On examination, child had difficulty in tracking objects and inferior field defect with preference for superior gaze. She was prescribed spectacles and visual stimulation exercises to preserve existing vision and prevent amblyopia. Periventricular leukomalacia can affect full-term infants although it is more common in preterm and LBW infants. All preterm, LBW infants, and those with positive neuroradiological findings must be assessed by an ophthalmologist as early as possible to detect the associated ocular manifestations.
More Related Videos
07:50A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
05:56Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016