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Pinching-off of Coated Vesicles01:32

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Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
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Related Experiment Video

Updated: Feb 19, 2026

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Multiple white dots on posterior capsule.

Chidanand Kulkarni1

  • 1Department of Ophthalmology, KMC, Manipal, Karnataka, India.

Oman Journal of Ophthalmology
|November 10, 2017
PubMed
Summary
This summary is machine-generated.

A unique case of unilateral cataract presented with unusual posterior capsular opacities. Despite the extensive opacities, the patient achieved excellent visual acuity after intraocular lens implantation.

Keywords:
Cataract in youngmultiple white dotsposterior capsular plaque

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Area of Science:

  • Ophthalmology
  • Surgical Case Report

Background:

  • A 38-year-old female presented with unilateral cataract without apparent predisposing factors.
  • Cataract surgery is a common procedure, but unexpected findings can occur.

Observation:

  • During cataract extraction, numerous uniform white dots were observed on the inner posterior capsule.
  • These opacities were widespread, covering the entire posterior capsule up to the equator.

Findings:

  • The patient's visual outcome was favorable, with Uncorrected Corrected Visual Acuity (UCVA) of 6/9 and Best Corrected Visual Acuity (BCVA) of 6/6 at six weeks.
  • Despite the extensive and peculiar capsular opacities, good visual function was achieved.

Implications:

  • This case highlights the importance of careful observation during cataract surgery.
  • It suggests that certain capsular opacities may not significantly impair visual outcomes.
  • Further investigation into the etiology and management of such unique capsular changes may be warranted.