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Panfolliculoma: A Clinical Case Report.

Roberto Estrada-Castañón1, María Elisa Vega-Memije2, Juan Carlos Cuevas-González3

  • 1Department of Dermatology, "Hospital General of Acapulco", Acapulco, Guerrero, Mexico.

International Journal of Trichology
|November 10, 2017
PubMed
Summary

Panfolliculoma is a rare benign neoplasm with follicular differentiation, presenting as comedo-like eyelid lesions. Clinicopathological correlation is crucial for distinguishing it from similar conditions like trichoblastoma.

Keywords:
Follicular differentiationpanfolliculomarare benign neoplasm

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Area of Science:

  • Dermatopathology
  • Oncology

Background:

  • Panfolliculoma is a rare benign neoplasm originating from follicular structures.
  • It shares morphological similarities with trichoblastoma but exhibits enhanced follicular differentiation.

Observation:

  • A 55-year-old female presented with pruritic, comedo-like lesions on the eyelids.
  • Dermatological examination revealed symmetrical papulonodular neoformations, comedones, and redundant skin affecting both upper and lower eyelids.

Findings:

  • Histopathological analysis showed an atrophic epidermis and dermis infiltrated by a neoplastic proliferation.
  • The neoplasm featured cystic structures lined by infundibular epithelium of the internal root sheath.

Implications:

  • Accurate diagnosis of panfolliculoma requires careful clinicopathological correlation due to its resemblance to trichoblastoma.
  • Understanding these rare follicular neoplasms aids in precise dermatological diagnosis and patient management.