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Novel Distal Emboli Protection Technology: The EmboTrap
Ju-Yu Chueh1, Miklos G Marosfoi1, Olivia W Brooks1
1New England Center for Stroke Research, Department of Radiology, University of Massachusetts, Worcester, Massachusetts, USA.
Interventional Neurology
|November 10, 2017
Summary
The EmboTrap thrombectomy system significantly reduced large emboli formation compared to older devices. This new stent retriever design may lower the risk of distal embolization during mechanical thrombectomy procedures.
Area of Science:
- Neurology
- Biomedical Engineering
- Interventional Radiology
Background:
- Mechanical thrombectomy for stroke can cause clot fragmentation and distal embolization.
- The EmboTrap system's design may mitigate clot fragmentation during endovascular procedures.
- Device design is hypothesized to influence emboli generation during thrombectomy.
Purpose of the Study:
- To evaluate the EmboTrap thrombectomy system's efficacy in reducing distal emboli.
- To compare emboli generation between EmboTrap and a first-generation stent retriever (Solitaire).
- To test if device design impacts emboli formation during mechanical thrombectomy.
Main Methods:
- An in vitro model simulating middle-cerebral artery occlusion was used.
- Embolization was assessed using EmboTrap and Solitaire thrombectomy systems.
- Emboli >1,000 μm were measured with calipers; emboli 200-1,000 μm were analyzed using the Coulter principle.
Main Results:
- EmboTrap significantly reduced the formation of large emboli (>1,000 μm) compared to first-generation stent retrievers (p=0.031).
- Most large emboli (>1,000 μm) were found in the middle cerebral artery, irrespective of the device used.
- EmboTrap demonstrated a significant size reduction of all emboli (>200 μm) (p=0.022).
Conclusions:
- Stent retriever design can modify the risk of distal embolization.
- The EmboTrap thrombectomy system may reduce distal embolization risk, particularly with fragment-prone clots.
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