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Updated: Feb 19, 2026
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Published on: March 12, 2018
Pulmonary metastasectomy in uterine malignancies: outcome and prognostic factors
Marco Anile1, Sara Mantovani1, Ylenia Pecoraro1
1University of Rome Sapienza, Policlinico Umberto I Viale del Policlinico, Rome, Italy.
Background:
This retrospective study is designed to evaluate factors affecting survival in a population of patients receiving pulmonary metastasectomy after gynecologic cancers.
Methods:
Nineteen patients with isolated lung metastases (one or two) were surgically treated with R0 resection. Four of them underwent lobectomies.
Results:
Six patients (31.6%) received adjuvant therapy and 11 (58%) experienced recurrences after metastasectomy. Five- and ten-year survival were 40.9% and 31.4%, respectively. Five-year survival in patients receiving adjuvant therapy was 52.4%. At multivariate analysis factors negatively influencing survival were a disease-free interval (DFI) of less than 24 months and recurrence after pulmonary metastasectomy.
Conclusions:
Pulmonary resection for metastatic gynecologic cancer is feasible and effective; adequate selection of patients is mandatory to achieve satisfactory results and long-term survival.
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