Pediatric inhalation injury

Soman Sen1

  • 1Division of Burn Surgery, Department of Surgery, University of California Davis, Shriners Hospital for Children Northern California, Sacramento, USA.

Burns & Trauma
|November 10, 2017
PubMed

Insights

Smoke inhalation injury significantly impacts pediatric cardiac and pulmonary function. This review covers injury pathology, early management, ventilation strategies, and long-term outcomes in children.

Area of Science:

  • Pediatric critical care medicine
  • Respiratory medicine
  • Toxicology

Background:

  • Smoke inhalation injury (SII) presents significant physiological challenges in children.
  • Pediatric patients experience profound cardiac and pulmonary changes following SII.
  • Understanding these complex physiological perturbations is crucial for effective management.

Purpose of the Study:

  • To review the pathology of smoke inhalation injury in pediatric patients.
  • To discuss early management strategies and current ventilator approaches for pediatric SII.
  • To examine the long-term outcomes associated with smoke inhalation injury in children.

Main Methods:

  • Comprehensive literature review of pediatric smoke inhalation injury.
  • Analysis of existing data on pathophysiology and clinical management.
  • Synthesis of information on ventilator strategies and patient outcomes.

Main Results:

  • SII induces severe systemic and organ-specific physiological disturbances in children.
  • Prompt recognition and tailored management are critical for mitigating acute complications.
  • Ventilator strategies must be adapted to the specific needs of pediatric patients with SII.

Conclusions:

  • Effective management of pediatric smoke inhalation injury requires a multidisciplinary approach.
  • Optimizing early interventions and ventilation can improve patient outcomes.
  • Further research into long-term sequelae is warranted to enhance pediatric care.

Related Concept Videos

Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
3.9K
Inhaled Medications01:23

Inhaled Medications

Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
862
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
1.2K
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
1.6K
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
743
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
953