[Optical coherence tomography in neuromyelitis optica spectrum disorders]

Area of Science:

• Neuroimmunology
• Ophthalmology
• Neuroscience

Background:

• Neuromyelitis optica spectrum disorders (NMOSD) are inflammatory CNS conditions.
• Optic neuritis (ON) is a common initial manifestation, leading to visual impairment.
• The retina is increasingly recognized as a CNS component relevant to NMOSD.

Purpose of the Study:

• To review the principles of optical coherence tomography (OCT).
• To describe the relevance of OCT in diagnosing NMOSD.
• To evaluate OCT's role in assessing NMOSD disease progression.

Main Methods:

• Review of optical coherence tomography (OCT) principles.
• Analysis of OCT's diagnostic and prognostic capabilities in NMOSD.
• Examination of OCT for detecting intraretinal pathologies in NMOSD.

Main Results:

• OCT is an effective method for NMOSD diagnostics and disease course evaluation.
• OCT demonstrates severe damage to the visual system from ON.
• OCT identifies NMOSD-specific intraretinal pathologies.

Conclusions:

• OCT is crucial for NMOSD diagnosis and monitoring.
• OCT findings in the retina offer insights into disease mechanisms.
• OCT may guide future differential diagnostics and therapeutic strategies for NMOSD.