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Updated: Feb 19, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
Necrotizing Microascus tracheobronchitis in a bilateral lung transplant recipient
Olivier Taton1, Benjamin Bernier1, Isabelle Etienne1
1Department of Pneumology, CUB-Erasme, Université Libre de Bruxelles, Brussels, Belgium.
A rare Microascus cirrosus fungal infection occurred in a lung transplant recipient despite antifungal treatment. A combination therapy including antifungals and endoscopic debridement led to a favorable outcome.
Area of Science:
- Mycology
- Transplant Medicine
- Infectious Diseases
Background:
- Invasive fungal infections pose a significant mortality risk in solid organ transplant recipients.
- Scopulariopsis species and their teleomorph Microascus are molds commonly found in soil and decaying organic matter.
- Infections caused by Microascus species are rare but life-threatening in immunocompromised patients due to inherent resistance to many antifungal drugs.
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