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Updated: Feb 19, 2026

An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
A case report of primary pancreatic leiomyosarcoma requiring six additional resections for recurrences
Shinichiro Makimoto1, Kotaro Hatano1, Naoki Kataoka1
1Department of Surgery, Kishiwada Tokushukai Hospital, Osaka, Japan.
Introduction:
Primary pancreatic leiomyosarcoma is extremely rare. We report a case in which six additional resections were required to treat recurrent tumors in a 5-year period following the primary operation.
Presentation Of Case:
A 69-year-old man presented with a pancreatic tumor. Abdominal computed tomography scan showed a large heterogeneous mass with a necrotic area arising from the pancreatic body. We performed distal pancreatectomy, splenectomy, and wide resection of the transverse mesocolon. Histopathological examination confirmed the diagnosis of a pancreatic leiomyosarcoma. We repeatedly performed surgery on recurrent tumors.
Discussion:
Primary pancreatic leiomyosarcoma is considered to be a highly aggressive malignancy. The most effective treatment is complete surgical resection with tumor-free margins. Even when tumors recur, it is possible to improve the prognosis by further resection.
Conclusion:
Long-term survival is achievable by repeated resection of recurrent tumors.
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