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Related Concept Videos

Ultrasonography01:17

Ultrasonography

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Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: Feb 19, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

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Imaging in cutaneous surgery.

Amanda Levine1,2,3, Daniel Siegel2,3, Orit Markowitz1,2,3

  • 1Department of Dermatology, Mount Sinai Medical Center, New York, NY, 10029, USA.

Future Oncology (London, England)
|November 11, 2017
PubMed
Summary
This summary is machine-generated.

Noninvasive imaging can improve skin cancer diagnosis and Mohs surgery efficiency. These techniques help delineate tumor margins before surgery and detect residual cancer in real-time after removal.

Keywords:
Mohs micrographic surgeryRaman spectroscopyfluorescence confocal microscopyhigh-frequency ultrasoundnoninvasive imagingoptical coherence tomographyreflectance confocal microscopyskin cancer

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Area of Science:

  • Oncology
  • Surgical Pathology
  • Medical Imaging

Background:

  • Skin cancer is the most common cancer in the USA, with increasing global incidence.
  • Mohs micrographic surgery offers precise tumor removal with maximal tissue and cosmetic preservation.
  • Rising skin cancer rates necessitate more efficient and cost-effective treatment strategies.

Purpose of the Study:

  • To explore the potential of noninvasive imaging technologies in enhancing the diagnosis and surgical management of skin cancers.
  • To assess the utility of in vivo and ex vivo imaging for improving the efficacy of Mohs micrographic surgery.

Main Methods:

  • Review of current noninvasive imaging modalities applicable to skin cancer.
  • Evaluation of in vivo imaging for pre-operative margin delineation.
  • Assessment of ex vivo imaging for real-time, post-excision margin analysis.

Main Results:

  • Noninvasive imaging devices can accurately delineate lateral and deep tumor margins prior to Mohs surgery.
  • Ex vivo imaging allows for rapid, virtually real-time detection of residual tumor after tissue excision.
  • These imaging techniques show promise in increasing the time and cost-effectiveness of skin cancer treatment.

Conclusions:

  • Noninvasive imaging represents a significant advancement in the surgical management of skin cancer.
  • Integrating these technologies into Mohs micrographic surgery workflows can improve diagnostic accuracy and treatment efficiency.
  • Further development and clinical adoption of noninvasive imaging are expected to optimize skin cancer care.