Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between fresh frozen plasma transfusion and mortality stratified by Glasgow Coma Scale scores in isolated traumatic brain injury: a nationwide cohort study in Japan.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2026
Same author

CT-first resuscitation for severe blunt trauma: A propensity score-matched cohort study.

The journal of trauma and acute care surgery·2026
Same author

The Association Between Signs of Life and Outcomes in Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis.

Acute medicine & surgery·2026
Same author

Effects of descending aortic occlusion for massive obstetric hemorrhage: Nationwide analysis of maternal death in Japan.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same author

Association between high ratio of platelet concentrate to red blood cell and survival among massively transfused patients.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2026
Same author

Noninvasive respiratory support strategies in chest trauma: A systematic review and network meta-analysis.

The journal of trauma and acute care surgery·2026

Related Experiment Video

Updated: Feb 19, 2026

Author Spotlight: Insight Into Innovations in Spinal Cord Injury Research
06:31

Author Spotlight: Insight Into Innovations in Spinal Cord Injury Research

Published on: January 19, 2024

2.9K

Model for predicting the injury severity score.

Shuichi Hagiwara1,2, Kiyohiro Oshima1,2, Masato Murata1,2

  • 1Department of Emergency Medicine Gunma University Graduate School of Medicine Maebashi Gunma Japan.

Acute Medicine & Surgery
|November 11, 2017
PubMed
Summary

A new formula using mean blood pressure and fibrin degradation products can predict injury severity scores in trauma patients. This tool offers a simple method for emergency department assessments.

Keywords:
Biomarkerfibrin degradation products (FDP)injury severity score (ISS)multiple linear regression analysistrauma

More Related Videos

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
11:28

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials

Published on: May 18, 2015

13.0K
A Contusion Model of Severe Spinal Cord Injury in Rats
10:00

A Contusion Model of Severe Spinal Cord Injury in Rats

Published on: August 17, 2013

31.4K

Related Experiment Videos

Last Updated: Feb 19, 2026

Author Spotlight: Insight Into Innovations in Spinal Cord Injury Research
06:31

Author Spotlight: Insight Into Innovations in Spinal Cord Injury Research

Published on: January 19, 2024

2.9K
A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
11:28

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials

Published on: May 18, 2015

13.0K
A Contusion Model of Severe Spinal Cord Injury in Rats
10:00

A Contusion Model of Severe Spinal Cord Injury in Rats

Published on: August 17, 2013

31.4K

Area of Science:

  • Trauma research
  • Emergency medicine
  • Clinical prediction modeling

Background:

  • Accurate assessment of injury severity is crucial for effective trauma patient management.
  • Existing methods for determining injury severity score (ISS) may require extensive data not readily available in the emergency department.
  • Development of a predictive formula using accessible parameters is needed.

Purpose of the Study:

  • To develop a predictive formula for the Injury Severity Score (ISS) using parameters available upon emergency department arrival.
  • To identify key clinical and laboratory variables that correlate with injury severity.

Main Methods:

  • Retrospective review of trauma patient records from Gunma University Hospital (January 2010 - December 2010).
  • Inclusion of 122 patients, analyzing parameters like mean blood pressure, Glasgow Coma Scale, and various blood markers.
  • Multiple linear regression analysis was employed to establish the predictive formula for ISS.

Main Results:

  • A predictive formula was derived: ISS = 13.252 - 0.078(mean blood pressure) + 0.12(fibrin degradation products).
  • The formula demonstrated statistical significance (P < 0.001) with a multiple correlation coefficient (R) of 0.739 (R² = 0.546).
  • The model explained approximately 54.6% of the variance in injury severity.

Conclusions:

  • A practical formula for predicting injury severity score in trauma patients has been developed.
  • The formula utilizes readily obtainable parameters (mean blood pressure, fibrin degradation products), facilitating rapid assessment in emergency settings.
  • This predictive tool can aid clinicians in initial trauma patient evaluation and management decisions.