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Protein intake and kidney function in humans: its effect on 'normal aging'.

M Blum¹, M Averbuch, Y Wolman

¹Department of Nephrology, Rokach Hospital, Tel Aviv, Israel.

Archives of Internal Medicine

|January 1, 1989

Summary

Dietary protein intake does not significantly impact kidney function during normal aging in healthy individuals. A low-protein diet, while beneficial for diseased kidneys, shows no added advantage for healthy aging kidneys.

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Area of Science:

Nephrology
Nutritional Science
Gerontology

Background:

Kidney function naturally declines with age.
Dietary protein intake is a known factor influencing kidney health, particularly in kidney disease.

Purpose of the Study:

To investigate the effect of dietary protein on kidney function in healthy aging subjects.
To compare kidney function between individuals on normal protein diets and those on long-term low-protein diets.

Main Methods:

Creatinine clearance was used to assess kidney function.
Study included healthy subjects on unrestricted protein diets and vegetarians on low-protein diets.

Main Results:

Both groups exhibited similar kidney function.

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Both groups showed comparable rates of age-related decline in renal function.

Low-protein diet did not alter kidney function in healthy aging.

Conclusions:

Dietary protein restriction does not significantly affect kidney function in healthy individuals during normal aging.
Low-protein diets are therapeutically important for diseased kidneys but not for healthy aging kidneys.