Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

922
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
922
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1.2K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.2K
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

740
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
740

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Parents' perceptions of barriers and facilitators to the implementation of augmentative and alternative communication: A qualitative meta-synthesis.

International journal of speech-language pathology·2026
Same author

Effectiveness of a 6-week occupational therapy program with hippotherapy on postural control and social behavior for children with autism spectrum disorder.

International journal of developmental disabilities·2026
Same author

The Standardization of the NATO Dental Fitness Categorization Template Against Dental Diseases, Within the United Kingdom Armed Forces.

Military medicine·2026
Same author

Belantamab mafodotin-associated keratopathy: Clinical outcomes and management from two UK tertiary centres.

British journal of haematology·2026
Same author

Continuity of care after bariatric surgery in Australia: Perspectives of general practitioners and patients.

Obesity research & clinical practice·2026
Same author

Recent Developments in United States Vaccine Policy: A Narrative Review.

Delaware journal of public health·2026

Related Experiment Video

Updated: Feb 19, 2026

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
08:33

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

14.0K

Subtle Microbiome Manipulation Using Probiotics Reduces Antibiotic-Associated Mortality in Fish.

Victor Schmidt1,2, Marta Gomez-Chiarri3, Chelsea Roy3

  • 1Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island, USA.

Msystems
|November 11, 2017
PubMed
Summary

Prophylactic antibiotics in aquaculture increase fish mortality by disrupting their microbiome. Probiotic treatments effectively restored disease resistance in black molly fish, offering a solution to antibiotic-induced susceptibility.

Keywords:
BacillusPhaeobacterVibrioantibioticsaquaculturecolonization resistancemicrobial ecologymicrobiomeprobiotics

More Related Videos

Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment
09:25

Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment

Published on: February 22, 2017

8.0K
Author Spotlight: Establishing Germ-Free Zebrafish for Microbiota-Host Relationship Studies
05:38

Author Spotlight: Establishing Germ-Free Zebrafish for Microbiota-Host Relationship Studies

Published on: April 12, 2024

2.3K

Related Experiment Videos

Last Updated: Feb 19, 2026

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
08:33

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

14.0K
Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment
09:25

Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment

Published on: February 22, 2017

8.0K
Author Spotlight: Establishing Germ-Free Zebrafish for Microbiota-Host Relationship Studies
05:38

Author Spotlight: Establishing Germ-Free Zebrafish for Microbiota-Host Relationship Studies

Published on: April 12, 2024

2.3K

Area of Science:

  • Aquatic microbiology
  • Animal health
  • Disease ecology

Background:

  • Prophylactic antibiotics are common in aquaculture to prevent disease outbreaks.
  • Antibiotic use may disrupt host microbiomes, reducing disease resistance (colonization resistance).
  • This disruption could paradoxically increase disease susceptibility in fish.

Purpose of the Study:

  • To investigate the impact of antibiotics on fish mortality after pathogen challenge.
  • To determine if probiotic inoculations can reverse antibiotic-induced disease susceptibility.
  • To explore the effects of probiotics on fish microbiome structure and diversity.

Main Methods:

  • Antibiotic treatment and subsequent pathogen challenge in black molly (Poecilia sphenops).
  • Assessment of fish mortality rates.
  • Inoculation with candidate probiotic bacteria (Phaeobacter inhibens S4Sm and Bacillus pumilus RI06-95Sm).
  • Analysis of microbiome colonization and community structure.

Main Results:

  • Antibiotic treatment significantly increased fish mortality.
  • Probiotic bacteria successfully colonized black molly microbiomes.
  • Probiotic treatment reversed antibiotic-induced increases in mortality.
  • Probiotics did not alter overall microbiome community structure or diversity.

Conclusions:

  • Prophylactic antibiotic use in aquaculture may increase disease susceptibility in fish.
  • Probiotic interventions can restore disease resistance compromised by antibiotics.
  • Targeted probiotic additions can be effective for microbiome restoration without altering overall community structure.