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Updated: Feb 19, 2026

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
Published on: May 16, 2025
Management of acute severe ulcerative colitis in children
Vei Shaun Siow1, Riha Bhatt2, Kevin P Mollen3
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Abstract:
The incidence of pediatric-onset ulcerative colitis (UC) is rising. Children often present with a more severe disease phenotype as compared to adults with over a third requiring hospitalization for the management of acute severe ulcerative colitis (ASUC). Further, in pediatric patients presenting with inflammatory bowel disease (IBD) limited to the colon, a definitive diagnosis of UC vs. Crohn's disease is often unclear. Here, we review the unique aspects of pediatric ASUC including the epidemiology, diagnosis, medical, and surgical management of this disease.
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