Related Experiment Video
Updated: Feb 19, 2026

Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
Heart failure in dilated cardiomyopathy mimicking asthma triggered by pneumonia
Kenichi Tetsuhara1, Satoshi Tsuji1, Katsutoshi Nakano2
1Division of Emergency Service and Transport Medicine, National Center for Child Health and Development, Tokyo, Japan.
Insights
Heart failure is a rare cause of childhood wheezing. Early chest X-rays and cardiac evaluations are crucial for diagnosing heart failure in children presenting with fever and abnormal vital signs.
Area of Science:
- Pediatric Cardiology
- Pediatric Emergency Medicine
Background:
- Heart failure is an uncommon cause of wheezing in children.
- Dilated cardiomyopathy can lead to heart failure, sometimes presenting with high fever.
Observation:
- A 23-month-old girl presented with high fever, cough, wheezing, chest retraction, and tachycardia.
- Initial diagnosis was asthma triggered by pneumonia, but symptoms persisted.
- Chest X-ray showed left lower lung consolidation and a cardiothoracic ratio of 60%.
Findings:
- The patient was ultimately diagnosed with heart failure secondary to idiopathic dilated cardiomyopathy.
- The child was discharged without any lasting complications.
Implications:
- Heart failure should be considered in the differential diagnosis of pediatric wheezing, especially with abnormal vital signs.
- A chest X-ray is recommended for initial assessment.
- A cardiothoracic ratio >50% warrants further cardiac investigation with ECG and echocardiography.
- Awareness of cognitive bias is important in emergency care settings.
Abstract:
Heart failure is a rare cause of wheezing and may develop into a critical condition in children. Few cases report patients with heart failure, secondary to dilated cardiomyopathy, with high fever. A 23-month-old girl visited the emergency department with high fever, cough, first wheezing episode, chest retraction and tachycardia. The chest X-ray revealed consolidation on the left lower lung field; the cardiothoracic ratio was 60%. She was diagnosed with bronchial asthma triggered by pneumonia, which remained unchanged during four visits. Subsequently, she was diagnosed with heart failure in idiopathic dilated cardiomyopathy and discharged without sequelae. During the first wheezing episode in children with abnormal vital signs, heart failure should be considered in the differential diagnosis, and a chest X-ray should be performed. Additionally, when the cardiothoracic ratio is greater than 50%, 12-lead ECG and echocardiography should be performed. Moreover, cognitive bias should be considered in all emergency care unit situations.
Related Concept Videos
Cardiomyopathy II: Dilated Cardiomyopathy
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
Heart Failure III: Clinical Manifestations
Heart Failure II: Pathophysiology
Asthma-I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

