Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ultrasonography01:17

Ultrasonography

8.1K
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
8.1K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

4.3K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
4.3K
Gross Anatomy of Bone01:17

Gross Anatomy of Bone

9.9K
The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...
9.9K
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

545
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
545
Compact Bone01:27

Compact Bone

17.1K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
17.1K
Spongy Bone01:09

Spongy Bone

8.3K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
8.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of gastric cancer patient-derived organoids in precision medicine: Clinicians' perspective.

Stem cell reports·2026
Same author

MaxI-Net: A 3D AI Framework for CBCT-Based Maxillofacial Defect Reconstruction and Patient-Specific Implant Generation with Biomechanical Validation.

Bioengineering (Basel, Switzerland)·2026
Same author

Pneumococcal meningitis among hospitalised children after introduction of pneumococcal conjugate vaccine in India: a sentinel hospital surveillance (2019-2022).

The Lancet regional health. Southeast Asia·2026
Same author

Sustainable phosphorus delivery using advanced slow-release fertilizers: A review.

Journal of environmental management·2026
Same author

International practice patterns and perceptions of pressurised intraperitoneal aerosol chemotherapy for management of gastric cancer: A global clinician survey.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Introduction to Psychoradiology: Neuroimaging Biomarkers and Their Clinical Application in Psychiatry.

Seminars in roentgenology·2026

Related Experiment Video

Updated: Feb 19, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness

Published on: March 18, 2022

3.5K

Hypertrophic Osteoarthropathy on Bone Scintigraphy.

Harleen Kaur1, Mitchel Muhleman2, Helena R Balon2

  • 1Department of Diagnostic Radiology and Molecular Imaging, Oakland University and Beaumont Hospital, Royal Oak, Michigan harleen.kaur@beaumont.org.

Journal of Nuclear Medicine Technology
|November 12, 2017
PubMed
Summary

This case report details a lung cancer patient with hypertrophic osteoarthropathy, a bone disorder. Bone scintigraphy revealed the characteristic pattern, aiding diagnosis and management discussions.

Keywords:
bone scanhypertrophic osteoarthropathy (HOA)lung cancermolecular imagingoncology

More Related Videos

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
06:31

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis

Published on: October 6, 2023

3.2K
Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
07:32

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model

Published on: May 6, 2020

13.3K

Related Experiment Videos

Last Updated: Feb 19, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness

Published on: March 18, 2022

3.5K
Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
06:31

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis

Published on: October 6, 2023

3.2K
Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
07:32

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model

Published on: May 6, 2020

13.3K

Area of Science:

  • Oncology
  • Radiology
  • Rheumatology

Background:

  • Lung cancer is a prevalent malignancy.
  • Hypertrophic osteoarthropathy (HOA) is a rare paraneoplastic syndrome.
  • Bone scintigraphy is a key imaging modality in oncology.

Observation:

  • A patient with a history of lung cancer presented with symptoms suggestive of HOA.
  • Bone scintigraphy was performed to evaluate the skeletal findings.

Findings:

  • The bone scintigraphy demonstrated a typical pattern of hypertrophic osteoarthropathy.
  • This pattern included characteristic periostitis and joint effusions.

Implications:

  • This case highlights the importance of recognizing HOA in lung cancer patients.
  • Early diagnosis and management of HOA can improve patient quality of life.
  • Understanding the pathophysiology of HOA is crucial for effective treatment strategies.