Utility of ¹¹¹In-Cl₃ scintigraphy for differentiating bone marrow reconversion

Indium chloride (¹¹¹In-Cl₃) scintigraphy has been used to evaluate various hematological diseases for many years. However, there have been few reports on patients with bone marrow reconversion showing high uptake in ¹¹¹In-Cl₃ scintigraphy. Herein, we report a case of a 68-year-old man with esophageal cancer who underwent ¹⁸F-FDG PET/CT for staging of the disease. ¹⁸F-FDG PET/CT demonstrated high uptake in the first lumbar vertebral body, which was difficult to distinguish bone metastasis and bone marrow reconversion. ¹¹¹In-Cl₃ scintigraphy demonstrated specific findings with high uptake in the lesion, indicating bone marrow hyperplasia or reconversion.