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Related Experiment Video

Updated: Feb 19, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Is there any role for minimally invasive surgery in NET?

M Thomaschewski1, H Neeff2, T Keck1

  • 1Department of Surgery, University of Lübeck and University Medical Center Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.

Reviews in Endocrine & Metabolic Disorders
|November 12, 2017
PubMed
Summary

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Laparoscopic surgery is increasingly used for neuroendocrine tumors (NET), but its superiority over traditional methods requires more evidence. This review examines current laparoscopic techniques for various NET, including adrenal, pancreatic, and intestinal types.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Neuroendocrine tumors (NET) exhibit a wide range of behaviors, from benign to malignant with metastatic potential.
  • Surgical resection is the primary treatment for NET, often guided by expert recommendations due to the rarity of the condition and limited prospective studies.
  • The rarity of NET poses challenges for developing and validating new surgical procedures.

Purpose of the Study:

  • To review the current application and evidence of laparoscopic techniques in the surgical treatment of neuroendocrine tumors (NET).
  • To explore recent advancements in minimally invasive surgery, including robotic-assisted and single-port surgery, for NET management.

Main Methods:

  • Literature review focusing on the current usage of laparoscopic techniques for adrenal, pancreatic, and intestinal NET.
Keywords:
AdrenalLaparoscopyLiverMinimally invasive surgeryNeuroendocrine tumorsPancreasRobotic surgery

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  • Inclusion of evidence for extraadrenal pheochromocytoma and neuroendocrine liver metastases treated with laparoscopic approaches.
  • Examination of recent developments in robotic-assisted and single-port surgery for NET.

    • Main Results:

    • Laparoscopic surgery is increasingly adopted for NET treatment, leveraging its known advantages.
    • Comparative data on the superiority of laparoscopic surgery for NET is limited and often inconclusive.
    • Evidence for laparoscopic procedures in adrenal, pancreatic, intestinal NET, and pheochromocytoma is presented.

    Conclusions:

    • Laparoscopic surgery is a growing modality for NET treatment, but robust comparative data is still needed.
    • Robotic-assisted and single-port surgery represent promising future directions for minimally invasive NET management.
    • Further research is essential to establish the definitive role and benefits of minimally invasive approaches in NET surgery.