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PET-Computed Tomography in Head and Neck Cancer: Current Evidence and Future Directions
Yin Jie Chen1, Tanya Rath2, Suyash Mohan3
1Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Hospital of the University of Pennsylvania, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Abstract:
Head and neck cancers are among the most common cancers worldwide. More than 90% to 95% are squamous cell carcinomas (SCCs). Accurate staging at diagnosis optimizes treatment planning with improved outcomes. Recently, 18F-fluorodeoxyglucose (FDG) PET-computed tomography (CT) has shown tremendous value at diagnosis for accurate staging, treatment planning, and prognostication; and after definitive therapy for assessing response and long-term surveillance. Novel non-FDG PET tracers are under investigation, which have great potential for improving patient care in this era of personalized medicine.
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