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Conjunctivochalasis: a systematic review.

Anna Marmalidou1, Ahmad Kheirkhah1, Reza Dana1

  • 1Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.

Survey of Ophthalmology
|November 13, 2017
PubMed
Summary
This summary is machine-generated.

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Conjunctivochalasis (CCH) involves loose conjunctival folds, often overlooked despite causing ocular discomfort, especially in the elderly. Treatments range from lubrication to surgical removal of excess tissue.

Area of Science:

  • Ophthalmology
  • Ocular Surface Disease

Background:

  • Conjunctivochalasis (CCH) is a common condition characterized by redundant conjunctival folds, frequently affecting the inferior bulbar conjunctiva.
  • It is a significant cause of ocular irritation and discomfort, particularly in the elderly population, yet often underdiagnosed.
  • Aging is the primary risk factor, though CCH can be associated with other ocular and nonocular conditions.

Purpose of the Study:

  • To review the clinical presentation, pathogenesis, and management of conjunctivochalasis.
  • To highlight the importance of recognizing CCH as a cause of ocular surface symptoms.
  • To discuss current treatment options, including medical and surgical interventions.

Main Methods:

  • Review of existing literature on conjunctivochalasis.
Keywords:
conjunctivaconjunctivochalasisdelayed tear clearancedry eye diseaseocular surface inflammation

Related Experiment Videos

  • Analysis of clinical observations regarding symptoms and risk factors.
  • Summary of reported histopathologic findings and treatment outcomes.

    • Main Results:

    • CCH can lead to symptoms of tear film instability and delayed tear clearance.
    • Pathogenesis is multifactorial, involving conjunctival aging, tear film issues, friction, and inflammation.
    • Histopathologic findings are inconsistent, with some studies showing normal microscopic structures.

    Conclusions:

    • Symptomatic CCH management includes lubrication and anti-inflammatory medications.
    • Surgical options like conjunctival cauterization or excision are considered for refractory cases.
    • Further research into the pathogenesis may improve understanding and treatment of this condition.