Related Experiment Videos
Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36
E Boyd1, A Theriault, J P Goddard
1Duncan Guthrie Institute of Medical Genetics, Glasgow, UK.
Human Genetics
|January 1, 1989
Abstract:
A gene for tRNAGlu has been assigned to human chromosome 1p36 by in situ hybridisation using a [3H]-labelled or biotinylated 2.4-kb (human) DNA fragment containing a tRNAGlu gene as a probe. With the biotinylated DNA probe a secondary statistically significant site of hybridisation was observed at 1q21-22 which might represent a pseudogene or related sequence. In fibroblasts from gorilla (Gorilla gorilla) using biotin labelling, a single site of hybridisation occurred at 1qter which provides further support for homology of 1q in the higher apes and human 1p.