Related Experiment Video
Updated: Feb 19, 2026

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
Prolonged uninterrupted sitting increases fatigue in type 2 diabetes
Paddy C Dempsey1, David W Dunstan2, Robyn N Larsen3
1Baker Heart and Diabetes Institute, Melbourne, VIC, Australia; Centre for Urban Transitions & Iverson Health Innovation Research Institute, Swinburne University of Technology, Melbourne, VIC, Australia.
Prolonged sitting significantly worsens fatigue in type 2 diabetes patients. Regularly interrupting sitting with short activity breaks can reduce this fatigue, potentially improving quality of life and self-care.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Clinical Trials
Background:
- Fatigue is a common and debilitating symptom for individuals with type 2 diabetes.
- This symptom negatively impacts daily functioning, including quality of life, work productivity, and diabetes self-management.
Purpose of the Study:
- To investigate the impact of prolonged uninterrupted sitting on fatigue levels in adults with type 2 diabetes.
- To compare fatigue experienced on days with continuous sitting versus days with interrupted sitting.
Main Methods:
- A randomized crossover trial design was employed.
- Participants with type 2 diabetes completed two conditions: prolonged uninterrupted sitting and sitting interrupted by brief activity breaks.
- Fatigue levels were assessed using a validated scale.
Main Results:
- Prolonged uninterrupted sitting led to a 29% relative increase in fatigue compared to interrupted sitting.
- The findings indicate a significant detrimental effect of sedentary behavior on fatigue in this population.
Conclusions:
- Regularly incorporating short activity breaks into the day can mitigate fatigue in type 2 diabetes.
- Reducing sedentary time may improve overall well-being and self-care adherence for individuals with type 2 diabetes.
Related Concept Videos
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Symptoms, Diagnosis, and Complications
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Psychoneuroimmunology: Diabetes and Cancer

