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Time and Factors Affecting the Direction of Re-drift in Essential Infantile Esotropia
Insights
Postoperative re-drift in infantile esotropia differs between exotropic and esotropic types. Early esotropic drift contrasts with late exotropic drift, influenced by preoperative factors and refractive changes.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Strabismus Surgery
Background:
- Infantile esotropia is a common childhood strabismus.
- Surgical correction aims to align the eyes and improve binocular function.
- Postoperative re-drift, including consecutive exotropia and recurrent esotropia, can occur after surgery.
Purpose of the Study:
- To investigate the distinct development patterns of postoperative re-drift in infantile esotropia.
- To identify associated factors contributing to consecutive exotropia and recurrent esotropia.
- To analyze the timing and predictors of different types of re-drift following surgical intervention.
Main Methods:
- A cohort of 112 patients with infantile esotropia, operated on before age 3, was retrospectively analyzed.
- Surgical outcomes were categorized into consecutive exotropia (>8 PD exodeviation), recurrent esotropia (>8 PD esodeviation), and monofixation syndrome (≤8 PD deviation).
- Occurrence rates, onset times, and associated factors of re-drift were evaluated using statistical analysis, including multinomial logistic regression.
Main Results:
- At a mean follow-up of 9.5 years, 33.0% developed consecutive exotropia and 38.4% developed recurrent esotropia.
- Recurrent esotropia primarily occurred within the first postoperative year (76.7%), while consecutive exotropia developed gradually over 10 years.
- Preoperative fixation preference and myopic progression rate predicted consecutive exotropia, whereas early postoperative esodeviation angle increase correlated with recurrent esotropia.
Conclusions:
- Significant differences exist in the temporal patterns of exotropic versus esotropic re-drift after infantile esotropia surgery.
- Preoperative assessment of fixation preference and refractive status, along with close postoperative monitoring, are crucial for predicting surgical outcomes.
- Understanding these distinct patterns aids in managing and optimizing long-term results for infantile esotropia.
Purpose:
To investigate the development pattern and related factors of postoperative re-drift in infantile esotropia.
Methods:
A total of 112 patients with infantile esotropia who underwent surgery before 3 years of age were included. Surgical outcomes were divided into (1) consecutive exotropia: more than 8 prism diopters (PD) of exodeviation; (2) recurrent esotropia: more than 8 PD of esodeviation; and (3) monofixation syndrome: maintenance of deviations within 8 PD. The occurrence rate, time of onset, and associated factors of the re-drift were evaluated.
Results:
At a mean follow-up of 9.5 years, consecutive exotropia developed in 37 patients (33.0%) and recurrent esotropia in 43 patients (38.4%). Whereas 76.7% of total recurrent esotropia cases were identified within postoperative 1 year, consecutive exotropia occurred constantly over 10 years postoperatively. The mean time to consecutive exotropia development from surgery was 78.6 months, greater than that of recurrent esotropia development (8.9 months) (P < 0.001). In multinomial logistic regression using monofixation syndrome as the reference category, fixation preference before surgery (odds ratio [OR]: 6.64, 95% confidence interval [CI]: 2.07 to 21.32) and the rate of myopic progression (OR: 15.07 per -1.00 D/year, 95% CI: 1.23 to 184.86) were associated with consecutive exotropia, whereas increase in the angle of esodeviation on postoperative day 1 (OR: 1.15, 95% CI: 1.04 to 1.26) was correlated with recurrent esotropia.
Conclusions:
This study demonstrates a difference between the development pattern of exotropic and esotropic drift after infantile esotropia surgery. Detailed preoperative assessment and close postoperative observation of deviations and refractive status will help to determine surgical outcomes of infantile esotropia. [J Pediatr Ophthalmol Strabismus. 2018;55(2):128-134.].
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