Tubeless versus standard percutaneous nephrolithotomy: an update meta-analysis

Area of Science:

• Urology
• Nephrology
• Surgical Innovation

Background:

• Systematic review and meta-analysis update on tubeless percutaneous nephrolithotomy (PCNL).
• Assessing the efficacy and safety of tubeless PCNL compared to traditional methods.

Purpose of the Study:

• To evaluate the effectiveness and safety of tubeless PCNL.
• To provide an updated evidence-based summary for clinical decision-making.

Main Methods:

• Systematic literature search across major databases (EMBASE, PubMed, Web of Science, Cochrane Library).
• Screening of scientific literature based on predefined inclusion/exclusion criteria.
• Meta-analysis of 14 randomized controlled trials (RCTs) involving 1148 patients using Stata SE 12.0.

Main Results:

• Tubeless PCNL showed significantly shorter operative time, hospital stay, and faster return to normal activity.
• Reduced postoperative pain scores, analgesia requirements, and urine leakage were observed.
• No significant differences in hemoglobin reduction, stone-free rate, fever, or transfusion rates were found.

Conclusions:

• Tubeless PCNL is a safe and effective option for selected patients.
• Associated with significant advantages including shorter recovery and reduced complications.
• Supports the adoption of tubeless PCNL in appropriate clinical scenarios.