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Published on: June 4, 2012
Perivalvular Mitral Abscess Fistulised to the Pericardial Cavity Revealing Staphylococcal Endocarditis
Paul Desaint1, Anthony Chauvat2, Thomas Garaud1
1Service de Réanimation Polyvalente, Centre Hospitalier Victor Dupouy, Argenteuil, France.
Background:
Fistula to the pericardial cavity is a very rare complication of perivalvular abscess during infective endocarditis, with Staphylococcus aureus being the most commonly associated microorganism.
Methods:
We report a fatal septic shock due to a mitral endocarditis revealed by a myocardial abscess fistulised toward the pericardial cavity.
Results:
A 66-year-old female without previous valvular disease was admitted to intensive care for severe sepsis. A few hours after admission, an unexpected cardiac arrest occurred. Chest computed tomographic-scan and transoesophageal echocardiography revealed a pericardial effusion due to a perivalvular mitral abscess fistulised toward the pericardial cavity. Despite prompt management including surgical debridement and appropriate antibiotics, death occurred 36hours after intensive care admission. All blood cultures as well as native mitral valve and pericardial fluid grew methicillin-sensitive Staphylococcus aureus.
Conclusions:
Intensivists should consider this rare complication in patients with staphylococcal infective endocarditis and perivalvular abscess.
Insights
A rare complication of infective endocarditis, a perivalvular abscess, can lead to a fistula to the pericardial cavity. Staphylococcus aureus was identified as the cause in a fatal case of mitral endocarditis.
Area of Science:
- Cardiology
- Infectious Diseases
- Critical Care Medicine
Background:
- Perivalvular abscesses in infective endocarditis can rarely form fistulas into the pericardial cavity.
- Staphylococcus aureus is frequently implicated in these severe cases.
Observation:
- A 66-year-old female presented with severe sepsis due to mitral endocarditis.
- An unexpected cardiac arrest occurred shortly after admission.
- Imaging revealed a perivalvular mitral abscess with a fistula to the pericardial cavity.
Findings:
- Despite aggressive treatment including surgery and antibiotics, the patient experienced a fatal outcome.
- Blood cultures, mitral valve tissue, and pericardial fluid all tested positive for methicillin-sensitive Staphylococcus aureus.
Implications:
- This case highlights a rare but potentially fatal complication of infective endocarditis.
- Clinicians, particularly intensivists, should maintain a high index of suspicion for this condition in patients with Staphylococcus aureus endocarditis and perivalvular abscesses.
Related Concept Videos
Endocarditis I: Introduction
Mitral Stenosis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Stenosis III: Medical Management
Pericarditis I: Introduction

