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Updated: Feb 18, 2026
Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Effect of low-level laser therapy on fracture healing in rabbits
Fahimeh Kamali Sarvestani1,2, Nasrin Salehi Dehno1, Seifollah Dehghani Nazhvani3
1School of rehabilitation, Shiraz University of Medical Sciences, Shiraz, Iran.
Background And Aims:
The purpose of this study was to investigate the effect of low-level laser therapy (LLLT) on radial bone fracture gap healing in a rabbit model.
Materials Subjects And Methods:
Thirty male white New Zealand rabbits under general anesthesia had a 3mm slice of radial bone surgically removed. Fifteen rabbits were treated by 830 nm laser at 4 J/cm2 and 15 were used as non-treated controls. Callus development was assessed by X-ray and radiographs every 7 days for 3 weeks.
Results:
Significant radiologic changes were observed in both groups against time (P > 0.001) or from week to week (P > 0.05). However, there was no statistical difference in radiologic scores after week 2 (P = 0.087) or week 3 (P = 0.077) between control and laser treated bone.
Conclusions:
Findings suggest that in this study, laser treatment did not enhance callus formation nor reduce repair time of complete fracture of the radius in rabbits.
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