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Updated: Feb 18, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
[Extragenital, disseminated infection with human papillomaviruses : Therapeutic response through vaccination with
L Wiskemann1, B Durani2, W Hartschuh2,3
1Haut- und Laserzentrum Dres. Durani, Bergheimerstr. 56a, 69115, Heidelberg, Deutschland. lea@wiskemann-online.de.
Abstract:
A 50-year-old man with widespread manifestation of warts and distinct pruritus for the last 5 years was diagnosed with a reactivated human papillomavirus (HPV) infection by three, genetically verified types (6, 16, 18), which are included in the vaccine Gardasil®. Conventional treatment was not successful, but a rapid and significant reduction of the skin manifestation was observed after vaccination with Gardasil®. To what extent therapy-resistant infections with HPV can be influenced through an active HPV vaccination should be investigated in future trials.
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