Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Synthetic Biology

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...

Biosynthesis in Bacteria

Biosynthesis in Bacteria

Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Biochemical Engineering Perspective on cGAS: From Enzyme Discovery to Potential Industrial Application.

Chembiochem : a European journal of chemical biology·2026

Same author

Engineering Pseudomonas taiwanensis VLB120 for regio- and stereospecific hydroxylation of L-lysine fueled by the Weimberg pathway.

Microbial cell factories·2026

Same author

Multidimensional strategy enables scalable metabolome diversity in microbial fermentations.

Scientific reports·2026

Same author

A Guide to Bayesian Optimization in Bioprocess Engineering.

Biotechnology and bioengineering·2026

Same author

Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies.

Chembiochem : a European journal of chemical biology·2025

Same author

Cell-free protein synthesis for biocatalysis.

Methods in enzymology·2025

Same journal

Valorization of Agricultural Residues Through Nutrient Enrichment for Animal Farming.

Advances in biochemical engineering/biotechnology·2026

Same journal

Safety Aspects of Cell Culture-Derived Food for Human Consumption.

Advances in biochemical engineering/biotechnology·2026

Same journal

Correction to: Perspectives Towards AI and ML.

Advances in biochemical engineering/biotechnology·2026

Same journal

Valorization of Agricultural Residues for Biohydrogen Production via Dark Fermentation.

Advances in biochemical engineering/biotechnology·2026

Same journal

Composting of Agricultural Residues into Organic Fertilizers for Sustainable Agriculture.

Advances in biochemical engineering/biotechnology·2026

Same journal

Correction to: Theoretical Perspectives for Biomolecular Crystallization Prediction.

Advances in biochemical engineering/biotechnology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 18, 2026

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

Enzyme-Based Electrobiotechnological Synthesis.

Lisa Marie Schmitz¹, Katrin Rosenthal¹, Stephan Lütz²

¹Department of Biochemical and Chemical Engineering, TU Dortmund University, Dortmund, Germany.

Advances in Biochemical Engineering/Biotechnology

|November 15, 2017

Summary

This summary is machine-generated.

Electrochemical regeneration of oxidoreductase cofactors offers an efficient method for organic synthesis. This review explores electroenzymatic strategies and reaction engineering to enhance productivity in biotransformations.

Keywords:

Cofactor regeneration Electrochemistry Electron mediator Enzyme catalysis Oxidoreductases Reactor design Rhodium complex

More Related Videos

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules

Published on: June 1, 2011

Related Experiment Videos

Last Updated: Feb 18, 2026

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules

Published on: June 1, 2011

Area of Science:

Biocatalysis and organic synthesis
Enzyme engineering and cofactor regeneration

Background:

Oxidoreductases are valuable enzymes for organic synthesis due to their high selectivity.
Efficient cofactor regeneration is crucial for oxidoreductase-driven biotransformations.
Electrochemical methods provide a mass-free and efficient approach for cofactor regeneration.

Purpose of the Study:

To provide an overview of electroenzymatic syntheses using oxidoreductases.
To analyze cofactor regeneration strategies within different enzyme subclasses.
To investigate methods for improving the productivity of electroenzymatic biotransformations.

Main Methods:

Review of direct and indirect electrochemical cofactor regeneration systems.
Categorization of electroenzymatic syntheses based on enzyme subclass and cofactor usage.
Analysis of reaction engineering concepts for productivity enhancement.

Main Results:

Various electrochemical regeneration methods (direct, indirect, electroenzymatic) have been investigated.
Electroenzymatic syntheses often face challenges with low productivity.
Key limiting factors include media conductivity, enzyme stability, and cell design.

Conclusions:

Electrochemical cofactor regeneration is a promising technique for oxidoreductase-based synthesis.
Optimizing reaction engineering is essential to overcome productivity limitations.
Advanced cell designs and strategies to prevent enzyme inactivation are crucial for practical applications.