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[The evidence for the efficiency and safety of dapoxetine in treating premature ejaculation]
N D Akhvlediani1, I P Matyukhov1
1I.M. Sechenov First MSMU of Minzdrav of Russia, Moscow, Russia.
Abstract:
The aim of the study is to assess the evidence on the efficacy and safety of dapoxetine in premature ejaculation (PE). The analysis includes results of randomized placebo-controlled trials, integrative reviews and one meta-analysis on the clinical efficacy and safety of dapoxetine. All studies have shown higher efficacy of dapoxetine in patients with PE compared with placebo. Its administration at a dosage of 30 and 60 mg results in an increase in the coitus duration up to approximately 3 and 3.5 minutes, respectively. The safety profile of dapoxetine allows using it in clinical practice. Dapoxetine is a novel and effective PE drug on the Russian market.
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