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Published on: May 10, 2021
Management of and risk factors for regional recurrence in upper lip squamous cell carcinoma
Fei Liu1, Lei Wang, Shuang Pang
1Department of Stomatology Department of Stomatology, School of Stomatoloy, Xinxiang Medical Collage, Xinxiang Department of Stomatology, Nanyang Stomatology Hospital, Nanyang Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Abstract:
Our goal was to evaluate the risk factors for regional recurrence in upper lip squamous cell carcinoma (SCC).A total of 109 patients with upper lip SCC were retrospectively enrolled. Clinical and pathologic information was collected and analyzed.Fifteen (13.8%) patients had a regional metastasis, 2 patients had parotid node metastasis, and no local or distant metastasis was noted. There was neck level I node metastasis in 15 (100%) patients. In multivariate analysis, invasion depth and degree of differentiation were significantly associated with regional metastasis. The 5- and 10-year disease-specific survival rate was 95.4% and 80.1%, respectively.Invasion depth and degree of differentiation have reliable value for predicting regional metastasis.

