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Updated: Feb 18, 2026

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids
Published on: October 14, 2019
Synchronous multiple carcinoma with small intestine and pulmonary neuroendocrine involvement: A case report
Binbin Shan1, Quanmao Zhang, Yuan Li
1Pneumology Department Endoscopy Center, Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi, China.
Rationale:
In clinical work, neuroendocrine synchronous multiplicity carcinoma was relatively rare. Most were confirmed by the pathological diagnosis of a certain part of the body combined with the imaging of the whole body, while cases that had both pathological and immunohistochemistry diagnosis were few.
Patient Concerns:
A patient who presented with abdominal pain visited our hospital, and was diagnosed with lesions in both the small intestine and lung.
Diagnoses:
Both were considered primary tumors by imaging, and diagnosed as neuroendocrine carcinomas by pathology.
Interventions:
The intestinal lesion was surgically resected, and the lung tumor treated by chemoradiotherapy.
Outcomes:
The survival time of this patient exceeded 24 months.
Lessons:
The diagnosis relied on clinical, imaging, pathological, and immunohistochemical features, which confirmed a synchronous multiple carcinoma. Treatment was based on the pathological types. Through this case report, the clinical and pathological data of neuroendocrine synchronous multiplicity carcinoma could be enriched.

