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Analysis on the risk factors of medication-overuse headache in Chinese patients
Junxia Li1, Chunfu Chen2, Ligong Zhang2
1Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, No. 324, Jingwu Road, Jinan, China; Department of Neurology, The Second People's Hospital of Liaocheng affiliated to Taishan Medical College, Shandong Linqing, China.
Objective:
The purpose of this study was to analyze the risk factors of medication-overuse headache in patients with chronic migraine in China.
Materials And Methods:
157 patients who were diagnosed as chronic migraine were chosen from headache outpatients of Shandong Provincial Hospital affiliated to Shandong University. Based on a standardized questionnaire, a database was developed and analyzed with 45 indexes.
Results:
The independent risk factors of medication-overuse headache identified in this study included the frequency of medicine overuse (OR = 9.575, 95%CI, 3.573-35.659), Allodynia Symptom Checklist scores (OR = 5.846, 95%CI, 2.065-22.856), anxiety disorder (OR = 2.902, 95%CI, 1.601-7.476) and lack or non- standardized preventive treatment (OR = 1.173, 95%CI, 1.073-3.826).
Conclusions:
The frequency of medicine overuse, Allodynia Symptom Checklist scores, anxiety disorder and lack or non-standardized preventive therapy were the independent risk factors for medication-overuse headache in patients with chronic migraine.
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