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Updated: Feb 18, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
A validated patient-specific FSI model for vascular access in haemodialysis
A M de Villiers1,2, A T McBride3,4, B D Reddy3
1Centre for Research in Computational and Applied Mechanics, University of Cape Town, Cape Town, South Africa. andiedevilliers@sun.ac.za.
Abstract:
The flow rate inside arteriovenous fistulas is many times higher than physiological flow and is accompanied by high wall shear stress resulting in low patency rates. A fluid-structure interaction finite element model is developed to analyse the blood flow and vessel mechanics to elucidate the mechanisms that can lead to failure. The simulations are validated against flow measurements obtained from magnetic resonance imaging data.
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