Cerebral Infarction and Refractory Seizures in a Neonate with Suspected Zika Virus Infection
1From the Touro College of Medicine, New York, New York; and Montefiore-Nyack Hospital, Nyack, New York.
The Pediatric Infectious Disease Journal
|November 16, 2017
Summary
Congenital Zika syndrome, a condition from prenatal Zika virus exposure, can cause severe neurological issues. This case highlights embolic stroke and intractable seizures in a neonate, potentially expanding the syndrome's definition.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Congenital Zika syndrome (CZS) encompasses birth defects linked to maternal Zika virus infection during gestation.
- The Zika virus can cross the placenta, leading to fetal anomalies.
Observation:
- A neonate born to a mother with suspected Zika virus infection presented with an embolic stroke.
- The infant also developed severe, medication-resistant seizures.
Findings:
- This case demonstrates a severe neurological presentation in a neonate associated with congenital Zika virus exposure.
- The occurrence of embolic stroke and intractable seizures expands the known spectrum of CZS.
Implications:
- This unique case may necessitate a revision of the diagnostic criteria for congenital Zika syndrome.
- Further research is warranted to understand the full range of neurological complications associated with prenatal Zika virus exposure.
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