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Epidemiology of type 1 diabetes in Polish children: A multicentre cohort study
Mieczysław Szalecki1,2, Marta Wysocka-Mincewicz1, Anna Ramotowska3
1Department of Endocrinology and Diabetology, Children's Memorial Health Institute, Warsaw, Poland.
Insights
Childhood type 1 diabetes (T1D) incidence rose by 50% in eastern and central Poland between 2010-2014. Urban children had higher T1D rates than rural children, with the largest increase observed in 10-14 year olds.
Area of Science:
- Pediatrics
- Endocrinology
- Epidemiology
Background:
- Childhood type 1 diabetes (T1D) incidence varies globally.
- Accurate incidence data are crucial for healthcare resource planning.
- This study focused on T1D incidence in Polish children.
Purpose of the Study:
- To assess the incidence of type 1 diabetes (T1D) in the pediatric population of eastern and central Poland.
- To identify trends and demographic variations in T1D incidence.
- To provide data for public health and resource allocation.
Main Methods:
- A cohort study design was employed.
- Data were collected from January 2010 to December 2014.
- Included children and adolescents under 18 with newly diagnosed T1D in eastern and central Poland (n=2174).
Main Results:
- Overall annual T1D incidence increased from 12.84/100,000 in 2010 to 18.46/100,000 in 2014 (1.5-fold increase).
- The incidence rate (IR) increased by 12.7% annually, with the lowest rise (7.1%) in 15-17 year olds.
- Urban incidence rates were significantly higher than rural rates (P < .02).
Conclusions:
- Childhood T1D incidence in eastern and central Poland increased 1.5-fold over five years.
- The highest incidence rise was observed in 10-14 year olds.
- Urban children exhibited significantly higher T1D rates compared to rural children.
Background:
The incidence of childhood type 1 diabetes (T1D) varies greatly between populations, and the estimates and/or predictions of the rates would aid in adequate planning of health care resources. The study's aim was to assess the incidence of T1D in the paediatric population of eastern and central Poland.
Methods:
In this cohort study covering the period from January 2010 to December 2014, data were collected for children and adolescents below 18 years of age with newly diagnosed T1D living in eastern and central Poland. A total of 2174 children were included in the analysis. The population estimates were from the Central Statistical Office of Poland.
Results:
Overall, the annual incidence of T1D increased from 12.84/100,000 in 2010 to 18.46/100,000 in 2014 with the incidence rate (IR) ratio of 1.5 (an increase in the IR by 12.7% per year over 5 years). The lowest increase in the IR by 7.1% per year was seen in 15 to 17-year-olds. In the urban population (age 0-17 years), the overall incidence rate was significantly higher than in subjects from rural communities (P < .02). The incidence of T1D in rural areas was significantly higher (p = .004) in voivodeships of higher population density. Such dependence was not observed in urban areas.
Conclusions:
The incidence of T1D in children living in eastern and central Poland increased 1.5-fold over the 5-year observation period with the highest rise in 10 to 14-year-olds and significantly higher rates in urban children compared with their peers living in rural areas.
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